Four out of every five House members who didn't side with their party on the health care bill represent districts that voted for the opposite party's presidential nominee in the 2008 election.

The party-buckers on the 220-215 vote on Saturday night included 39 Democrats who voted against the bill. Of them, 31 represent districts that voted for John McCain over Barack Obama. Republicans are targeting many of them for defeat in the 2010 election. Of the other eight, three are serving their first terms in districts in which they defeated or succeeded Republicans in the 2008 election.

Eighteen Democrats from McCain-voting districts backed the bill. Among this subset, seven-term Rep. Marion Berry of Arkansas represents the most pro-McCain district (59 percent). He's more politically secure than other "McCain Democrats" who voted for the bill, including first-term Rep. Tom Perriello of Virginia and second-term Rep. Zack Space of Ohio.

The conservative Family Research Council's political action committee plans to target 16 congressional races in 2010. The group's president, Tony Perkins, said the PAC has a goal of raising $1 million to boost grassroots activity in targeted races.

The group wants to spend money to help favored candidates take over the seats now represented by:

Sen. Michael Bennet, a Democrat who is running for a full term in Colorado after his appointment this year;

Sen. Christopher J. Dodd, a Democrat who is running for re-election in Connecticut;

New Hampshire Sen. Judd Gregg, a Republican who is retiring;

Missouri Sen. Christopher S. Bond, a Republican who is retiring;

Rep. John Boccieri, a Democrat who represents Ohio's 16th District;

While members of Congress are home for recess, the Pharmaceutical Research and Manufacturers of America (PhRMA) is using a $2.5 million ad campaign to boost the health care records of several potentially vulnerable House Democrats.

Television commercials began running June 27 in six members' home districts and will air for two weeks. Accompanying mailers were also sent to voters.

"On health care there are two sides of the coin. On one side, do nothing. On the other, move forward- like Congressman Jim Himes, who's making real progress on reform," said the voiceover in one targeted television ad. The commercial continues by crediting Himes for expanding coverage for children, veterans, and protecting Medicare.